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Masaomi Nangaku Selected Research

Anemia

12/2022Safety of daprodustat in patients with anemia of chronic kidney disease: A pooled analysis of phase 3 studies in Japan.
4/2022Two long-term phase 3 studies of enarodustat (JTZ-951) in Japanese anemic patients with chronic kidney disease not on dialysis or on maintenance hemodialysis: SYMPHONY ND-Long and HD-Long studies.
2/2022A phase 3, open-label, single-arm study of vadadustat for anemia in chronic kidney disease for Japanese patients on hemodialysis not receiving erythropoiesis-stimulating agents.
1/2022An evaluation of roxadustat for the treatment of anemia associated with chronic kidney disease.
12/2021Efficacy and safety of daprodustat in Japanese peritoneal dialysis patients.
11/2021A Phase 3 Study of Enarodustat (JTZ-951) in Japanese Hemodialysis Patients for Treatment of Anemia in Chronic Kidney Disease: SYMPHONY HD Study.
10/2021Vadadustat for anemia in chronic kidney disease patients on peritoneal dialysis: A phase 3 open-label study in Japan.
7/2021A Phase 3 Study of Enarodustat in Anemic Patients with CKD not Requiring Dialysis: The SYMPHONY ND Study.
5/2021Renal prognoses by different target hemoglobin levels achieved by epoetin beta pegol dosing to chronic kidney disease patients with hyporesponsive anemia to erythropoiesis-stimulating agent: a multicenter open-label randomized controlled study.
1/2021[Renal anemia and hypoxia-inducible factor prolyl hydroxylase inhibitor].
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Masaomi Nangaku Research Topics

Disease

107Hypoxia (Hypoxemia)
09/2022 - 07/2003
71Chronic Renal Insufficiency
12/2022 - 05/2006
52Anemia
12/2022 - 01/2006
32Proteinuria
01/2022 - 10/2001
29Diabetic Nephropathies (Diabetic Nephropathy)
09/2022 - 01/2002
27Neoplasms (Cancer)
12/2022 - 02/2008
27Acute Kidney Injury (Acute Renal Failure)
10/2022 - 03/2004
23Fibrosis (Cirrhosis)
01/2021 - 04/2002
22Type 2 Diabetes Mellitus (MODY)
06/2022 - 04/2008
21Inflammation (Inflammations)
09/2022 - 07/2006
19Kidney Diseases (Kidney Disease)
03/2022 - 10/2008
16Albuminuria
09/2022 - 08/2011
16Chronic Kidney Failure (Chronic Renal Failure)
01/2022 - 01/2002
14Hypertension (High Blood Pressure)
01/2020 - 05/2003
13Reperfusion Injury
11/2020 - 03/2004
13Ischemia
01/2020 - 03/2004
12Renal Insufficiency (Renal Failure)
06/2022 - 06/2004
11Infections
12/2021 - 02/2014
10Atypical Hemolytic Uremic Syndrome
01/2022 - 01/2014
9Glomerulonephritis
01/2022 - 01/2002
9Body Weight (Weight, Body)
01/2022 - 12/2005
9Thrombotic Microangiopathies
01/2020 - 10/2001
9Nephrotic Syndrome (Syndrome, Nephrotic)
12/2017 - 12/2004
8Cardiovascular Diseases (Cardiovascular Disease)
05/2022 - 06/2006
8Diabetes Mellitus
03/2022 - 01/2015
8Heart Failure
06/2020 - 10/2012
7Sepsis (Septicemia)
07/2020 - 01/2014
6Hyperglycemia
01/2021 - 12/2005
6Obesity
01/2020 - 12/2005
6Membranous Glomerulonephritis (Membranous Nephropathy)
02/2018 - 05/2005
6Nephritis
04/2015 - 01/2002
5Critical Illness (Critically Ill)
08/2020 - 01/2016
5Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
01/2020 - 07/2012
5Thrombosis (Thrombus)
01/2020 - 10/2001
4COVID-19
05/2022 - 08/2020
4Edema (Dropsy)
01/2022 - 01/2011
4Diarrhea
12/2021 - 12/2016
4Mitochondrial Diseases (Mitochondrial Disease)
01/2021 - 01/2019
4Ascites
02/2020 - 02/2014
4Insulin Resistance
01/2020 - 01/2015

Drug/Important Bio-Agent (IBA)

29Prolyl-Hydroxylase InhibitorsIBA
09/2022 - 12/2007
27Oxygen (Dioxygen)IBA
01/2022 - 01/2004
25Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2002
21ErythropoietinFDA Link
01/2021 - 01/2006
20CreatinineIBA
07/2022 - 08/2011
18Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
01/2021 - 01/2006
17Glucose (Dextrose)FDA LinkGeneric
07/2022 - 05/2003
16HematinicsIBA
02/2022 - 08/2013
16Complement System Proteins (Complement)IBA
01/2022 - 01/2002
15Hemoglobins (Hemoglobin)IBA
01/2022 - 07/2006
15Pharmaceutical PreparationsIBA
01/2022 - 02/2008
13Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 12/2004
12enarodustatIBA
04/2022 - 01/2019
11Biomarkers (Surrogate Marker)IBA
10/2022 - 01/2014
11Transcription Factors (Transcription Factor)IBA
02/2021 - 11/2005
10Darbepoetin alfa (Aranesp)FDA Link
02/2021 - 01/2015
9Advanced Glycation End ProductsIBA
09/2022 - 10/2002
9AlbuminsIBA
07/2022 - 03/2008
9SodiumIBA
07/2022 - 09/2011
9Messenger RNA (mRNA)IBA
01/2019 - 04/2004
8IronIBA
12/2021 - 12/2005
7GSK1278863IBA
12/2022 - 01/2017
7RNA (Ribonucleic Acid)IBA
10/2022 - 01/2002
7EnzymesIBA
10/2019 - 02/2008
6Antihypertensive Agents (Antihypertensives)IBA
07/2022 - 05/2003
6Sodium-Glucose Transporter 2 InhibitorsIBA
07/2022 - 01/2019
6Dipeptidyl-Peptidase IV InhibitorsIBA
05/2022 - 09/2011
6CytokinesIBA
01/2022 - 01/2011
6Blood Glucose (Blood Sugar)IBA
01/2021 - 08/2011
6Lipocalin-2IBA
08/2020 - 11/2013
6DNA (Deoxyribonucleic Acid)IBA
01/2020 - 05/2013
6CobaltIBA
01/2018 - 07/2003
6ElementsIBA
11/2011 - 12/2004
5empagliflozinIBA
06/2022 - 05/2019
5Insulin (Novolin)FDA Link
02/2022 - 05/2003
5vadadustatIBA
02/2022 - 07/2020
5Fibroblast Growth Factor-23IBA
01/2022 - 01/2017
5Small Interfering RNA (siRNA)IBA
12/2020 - 08/2015
5Histones (Histone)IBA
01/2020 - 01/2011
5eculizumabFDA Link
04/2019 - 07/2016
5SteroidsIBA
12/2017 - 10/2014
5cobaltous chloride (cobalt(II)chloride)IBA
04/2017 - 11/2011
5Angiotensin IIIBA
01/2015 - 02/2004
4bardoxolone methylIBA
09/2022 - 10/2019
4PotassiumIBA
07/2022 - 04/2017
4esaxerenoneIBA
07/2022 - 01/2019
4Phosphates (Orthophosphate)IBA
01/2022 - 01/2017
4Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2022 - 07/2015
4Cisplatin (Platino)FDA LinkGeneric
01/2021 - 11/2005
4Interleukin-6 (Interleukin 6)IBA
07/2020 - 12/2014
4ChloridesIBA
05/2020 - 05/2014
4Urea (Carbamide)FDA LinkGeneric
01/2020 - 10/2001
4Streptozocin (Streptozotocin)FDA Link
01/2020 - 05/2006

Therapy/Procedure

48Therapeutics
07/2022 - 04/2003
23Renal Dialysis (Hemodialysis)
04/2022 - 04/2003
10Peritoneal Dialysis
12/2021 - 09/2005
6Plasma Exchange
04/2019 - 07/2006
5Catheters
12/2021 - 10/2020
5Kidney Transplantation
03/2020 - 03/2004
5Continuous Renal Replacement Therapy
01/2019 - 04/2015